The most striking things running through this medicine are twitchings and tremblings. Jerkings of the muscles and trembling of the limbs; quivering and tremors, everywhere these two features are present in all parts of the body and limbs. The twitching of the muscles becomes so extensive that it is a well- developed case of chorea. It has in its nature all that is found in chorea and has cured many cases. This is a general belonging to all parts. To all muscles. Throughout the body there is a sensation of creeping and crawling. It is hardly confined to the skin, it is felt as if in the flesh, a sensation as if of ants. Itching of the skin all over which changes place from scratching. No place is exempt from this. There are strange sensations here and there upon the skin or in parts, cold sensations, sensations of cold needles and of hot needles, stinging and burning where the circulation is feeble, about the ears, nose, back of hands and fingers and toes, red spots with itching and burning as if frostbitten. It is a great remedy for chilblains. The patient is extremely nervous and sensitive to cold. Itching. pricking, tingling, etc., come on from mental exertion and are relieved from physical exertion. All the symptoms of Agaricus are also aggravated after sexual intercourse. especially in the symptoms of the spinal cord. It is useful for the symptoms which come on after coition in young, nervous married women, hysterical fainting after coition. The mental symptoms are such as you would expect. Great change-ability, irritability, mental depression and complaints which come on from over exertion of the mind and prolonged study. The brain seems to be developed tardily. Children are late in learning to talk and walk, thus combining the features of two remedies, Natrum muriaticum, which has the symptom "late learning to talk", and Calcarea carb., which has the symptom "late learning to walk". It will be noticed in Calcarea that this is due to a defect in bone weakness. In Agaricus it is a mental defect. a slowly developing mind. Children with twitching and early fainting, nervous girls prior to puberty who have convulsions from being scolded, from excitement and shock, late in mental development. Children who cannot remember, make mistakes and are slow in learning. Nervous patients who on going over their manuscripts find out their mistakes in writing and spelling. The condition of the mind is one in which they are slow to grasp ideas; wrong words float in kaleidoscopically. When we read in the book "the whole psychological sphere as if paralyzed", we must read between the lines. The whole mind and sensorium seem paralyzed; the patient is sluggish, stupid, at times seems to be delirious; there is confusion of the mind so nearly like delirium that it is not unlike intoxication. A delirium such as is produced by alcohol. He also becomes silly, says foolish and silly things, sings and whistles at an inopportune time, makes verses and prophesies; or he lapses into an opposite state, becomes indifferent to his surroundings. One who is mild and placid becomes self-willed, obstinate and conceited.